Journal article

Human lens weights with increasing age

Ashik Mohamed, Robert C Augusteyn

MOLECULAR VISION | MOLECULAR VISION | Published : 2018

Abstract

Purpose: To evaluate the changes with age in human lens wet and dry weights. Methods: All procedures were performed by the same person in the same environment. Lenses were extracted from donor eyes within a median post-mortem time of 22 h, blotted dry and weighed within 30 min, immediately placed in fixative for 1 week, and then dried at 80 °C until a constant weight was achieved. Results: Wet and dry lens weights were obtained from 549 human lenses. Before age 2 years, most of the weight increases are due to a self-limiting process and can be described with logistic equations. The maximum asymptotic wet and dry weights for male lenses are 6.0 and 1.77 mg, respectively, heavier than those fo..

View full abstract

Grants

Awarded by NIH


Awarded by NATIONAL EYE INSTITUTE


Funding Acknowledgements

This work was supported, in part, by NIH Research Grants R01EY021834 and P30EY14801 (Center Grant), Hyderabad Eye Research Foundation and the Australian Federal Government CRC Scheme through the Vision Cooperative Research Centre. We are indebted to the Ramayamma International Eye Bank, Hyderabad, India for the supply of eyes.