Intermittent Fasting with or without Exercise Prevents Weight Gain and Improves Lipids in Diet-Induced Obese Mice
Robin A Wilson, William Deasy, Christos G Stathis, Alan Hayes, Matthew B Cooke
NUTRIENTS | MDPI | Published : 2018
Intermittent fasting (IF) and high intensity interval training (HIIT) are effective lifestyle interventions for improving body composition and overall health. However, the long-term effects of IF and potential synergistic effects of combining IF with exercise are unclear. The purpose of the study was to investigate the long-term effects of IF, with or without HIIT, on body composition and markers of metabolic health in diet-induced obese mice. In a randosmised, controlled design, 8-week-old C57BL/6 mice (males (n = 39) and females (n = 49)) were fed a high fat (HF) and sugar (S) water diet (30% (w/v)) for 24-weeks but were separated into five groups at 12-weeks: (1) 'obese' baseline control ..View full abstract
R.A.W. is currently supported by Victoria University International Post-graduate research Scholarship. Authors would like to thank Anne Luxford, Animal facilities manager for her kind help in conducting animal work. Funds for covering the cost to publish open access were provided by university internal grant.