A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction
Klaartje Somers, Victoria W Wen, Shiloh MC Middlemiss, Brenna Osborne, Helen Forgham, MoonSun Jung, Mawar Karsa, Molly Clifton, Angelika Bongers, Jixuan Gao, Chelsea Mayoh, Newsha Raoufi-Rad, Eric P Kusnadi, Kate M Hannan, David A Scott, Alan Kwek, Bing Liu, Claudia Flemming, Daria A Chudakova, Ruby Pandher Show all
Oncogene | NATURE PUBLISHING GROUP | Published : 2019
Awarded by NCI Cancer Center Support Grant
This research was supported by NHMRC, Leukemia Foundation, Anthony Rothe Memorial Trust, NSW Cancer Council, Cancer Institute NSW, Tenix Foundation, ISG Foundation and the Children's Leukemia & Cancer Research Foundation, Perth. Metabolic analysis was performed at the Cancer Metabolism Core, SBP Medical Discovery Institute, with assistance from Olga Zagnitko and support of NCI Cancer Center Support Grant P30 CA30199.