Journal article
Overview of the BioCreative VI Precision Medicine Track: mining protein interactions and mutations for precision medicine
Rezarta Islamaj Dogan, Sun Kim, Andrew Chatr-aryamontri, Chih-Hsuan Wei, Donald C Comeau, Rui Antunes, Sergio Matos, Qingyu Chen, Aparna Elangovan, Nagesh C Panyam, Karin Verspoor, Hongfang Liu, Yanshan Wang, Zhuang Liu, Berna Altinel, Zehra Melce Husunbeyi, Arzucan Ozgur, Aris Fergadis, Chen-Kai Wang, Hong-Jie Dai Show all
Database | Oxford University Press | Published : 2019
Abstract
The Precision Medicine Initiative is a multicenter effort aiming at formulating personalized treatments leveraging on individual patient data (clinical, genome sequence and functional genomic data) together with the information in large knowledge bases (KBs) that integrate genome annotation, disease association studies, electronic health records and other data types. The biomedical literature provides a rich foundation for populating these KBs, reporting genetic and molecular interactions that provide the scaffold for the cellular regulatory systems and detailing the influence of genetic variants in these interactions. The goal of BioCreative VI Precision Medicine Track was to extract this p..
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Grants
Awarded by National Institutes of Health Office of Research Infrastructure Programs
Funding Acknowledgements
National Institutes of Health Intramural Research Program National Library of Medicine; National Institutes of Health Office of Research Infrastructure Programs (R01OD010929 and R24OD011194 to A.C.-a.).