Cardiovascular Risk Factor Burden in People With Incident Type 2 Diabetes in the US Receiving Antidiabetic and Cardioprotective Therapies
Olga Montvida, Xiaoling Cai, Sanjoy K Paul
DIABETES CARE | AMER DIABETES ASSOC | Published : 2019
OBJECTIVE: Individualized treatment of patients with diabetes requires detailed evaluation of risk factor dynamics at the population level. This study evaluated the persistent glycemic and cardiovascular (CV) risk factor burden over 2 years after treatment intensification (TI). RESEARCH DESIGN AND METHODS: From U.S. Centricity Electronic Medical Records, 276,884 patients with incident type 2 diabetes who intensified metformin were selected. Systolic blood pressure (SBP) ≥130/140 mmHg and LDL ≥70/100 mg/dL were defined as uncontrolled for those with/without a history of CV disease at TI. Triglycerides ≥150 mg/dL and HbA1c ≥7.5% (58 mmol/mol) were defined as uncontrolled. Longitudinal measures..View full abstract
Melbourne EpiCentre acknowledges support from the National Health and Medical Research Council and the Australian Government's National Collaborative Research Infrastructure Strategy initiative through Therapeutic Innovation Australia. O.M. acknowledges receipt of a PhD scholarship from Queensland University of Technology. No separate funding was obtained for this study.