Journal article

Single dose prednisolone alters endocrine and haematologic responses and exercise performance in men.

I Levinger, A Tacey, L Parker, BB Yeap, J Joseph, EM Lim, A Garnham, DL Hare, T Brennan-Speranza

Endocrine Connections | BioScientifica | Published : 2019


The aim of this study was to investigate the effect of a single dose of prednisolone on (A) high-intensity interval cycling performance and (B) post-exercise metabolic, hormonal and haematological responses. Nine young men participated in this double-blind, randomised, cross-over study. The participants completed exercise sessions (4 × 4 min cycling bouts at 90–95% of peak heart rate), 12 h after ingesting prednisolone (20 mg) or placebo. Work load was adjusted to maintain the same relative heart rate between the sessions. Exercise performance was measured as total work performed. Blood samples were taken at rest, immediately post exercise and up to 3 h post exercise. Prednisolone ingestion ..

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Awarded by Heart Foundation

Funding Acknowledgements

Itamar Levinger was supported by the Heart Foundation (ID: 100040). The authors wish to thank the men who participated in this study for their time and effort.