The distribution of estrogen receptors in the brainstem of female sheep

Abstract

Estrogen receptors (ER) have been mapped in the brainstem of the female sheep with immunocytochemistry. A small group of ER-positive cells was found in the lateral and ventrolateral medulla and a larger number in the nucleus of the solitary tract. ER-positive cells were abundant in the area postrema. In the rostral brainstem a small number of ER-positive cells were found in the lateral and dorsal regions of the periaqueductal gray area, and some immediately lateral to the fourth ventricle. Many ER-positive cells were also present in the region around the superior cerebellar peduncle, particularly in the lateral parabrachial nucleus. These results describe for the first time the distribution ..