THE TEMPORAL RELATIONSHIP BETWEEN GONADOTROPIN-RELEASING HORMONE (GNRH) AND LUTEINIZING-HORMONE (LH) SECRETION IN OVARIECTOMIZED EWES
IJ CLARKE, JT CUMMINS
ENDOCRINOLOGY | OXFORD UNIV PRESS INC | Published : 1982
Hypothalamo-hypophyseal portal blood has been collected from conscious OVX ewes by a procedure that permits maintenance of pituitary function. GnRH was measured in portal plasma and LH was measured in peripheral (jugular) plasma. The data demonstrate exact synchrony of GnRH and LH secretion. We conclude that each pulsatile LH secretory episode results from a pulsatile discharge of GnRH from the hypothalamus via the portal network. © 1982 by The Endocrine Society.