Dependency and health utilities in stroke: Data to inform cost-effectiveness analyses.
Myzoon Ali, Rachael MacIsaac, Terence J Quinn, Philip M Bath, David L Veenstra, Yaping Xu, Marian C Brady, Anita Patel, Kennedy R Lees
European Stroke Journal | Published : 2017
Introduction: Health utilities (HU) assign preference weights to specific health states and are required for cost-effectiveness analyses. Existing HU for stroke inadequately reflect the spectrum of post-stroke disability. Using international stroke trial data, we calculated HU stratified by disability to improve precision in future cost-effectiveness analyses. Materials and methods: We used European Quality of Life Score (EQ-5D-3L) data from the Virtual International Stroke Trials Archive (VISTA) to calculate HU, stratified by modified Rankin Scale scores (mRS) at 3 months. We applied published value sets to generate HU, and validated these using ordinary least squares regression, adjusting ..View full abstract