Journal article

Associations of mortality and cardiovascular disease risks with diabetes and albuminuria in urban Indigenous Australians: the DRUID follow-up study

ELM Barr, J Cunningham, S Tatipata, T Dunbar, N Kangaharan, S Guthridge, SQ Li, JR Condon, JE Shaw, K O'Dea, LJ Maple-Brown

DIABETIC MEDICINE | WILEY | Published : 2017

Abstract

AIM: To assess the relationships of diabetes and albuminuria with all-cause mortality and cardiovascular disease outcomes in a population without prior cardiovascular disease using data from the Darwin Region Urban Indigenous Diabetes (DRUID) study. METHODS: We conducted a prospective cohort study of 706 participants (aged 15-81 years, 68% women) without prior cardiovascular disease who underwent a 75-g oral glucose tolerance test. Deaths and fatal or non-fatal cardiovascular disease were determined over 7 years, and hazard ratios with 95% CIs and population attributable risks were estimated for baseline glycaemia and albuminuria. RESULTS: Compared with normoglycaemia and after adjustment fo..

View full abstract

Grants

Awarded by National Health and Medical Research Council (NHMRC) Training Research Fellowship


Awarded by NHMRC Senior Research Fellowship


Awarded by NHMRC Practitioner Fellowship


Awarded by NHMRC Project Grant


Awarded by NHMRC programme grant


Funding Acknowledgements

E.L.M.B. is supported by a National Health and Medical Research Council (NHMRC) Training Research Fellowship (APP1016612); J.C. is supported by a NHMRC Senior Research Fellowship (#1058244 and #545200); L.M.-B. is supported by a NHMRC Practitioner Fellowship (#1078477); J.E.S. is supported by a NHMRC Senior Research Fellowship (APP 1079438). The baseline DRUID study was funded by NHMRC Project Grant (236207), with additional support from the Australian Government Department of Employment and Workplace Relations, the Clive and Vera Ramaciotti Foundation, the Vincent Fairfax Family Foundation, the International Diabetes Institute (AusDiab Partnership), and Bayer HealthCare, and was an in-kind project of the Cooperative Research Centre for Aboriginal Health. The DRUID follow-up study was funded by a Diabetes Australia Research Trust General Grant, a Northern Territory Research and Innovation Board Grant, and an NHMRC programme grant (631947), and in-kind support was provided by the Northern Territory Department of Health. Funding sources played no role in the study design, in the collection, analysis and interpretation of the data, in the writing of the manuscript, or in the decision to submit the manuscript for publication.