Stereotactic Radiotherapy as a Treatment Option for Renal Tumors in the Solitary Kidney: A Multicenter Analysis from the IROCK

RJM Correa; AV Louie; M Staehler; A Warner; S Gandhidasan; L Ponsky; R Ellis; I Kaplan; A Mahadevan; W Chu; A Swaminath; H Onishi; BS Teh; SS Lo; A Muacevic; S Siva

Journal article

Stereotactic Radiotherapy as a Treatment Option for Renal Tumors in the Solitary Kidney: A Multicenter Analysis from the IROCK

RJM Correa, AV Louie, M Staehler, A Warner, S Gandhidasan, L Ponsky, R Ellis, I Kaplan, A Mahadevan, W Chu, A Swaminath, H Onishi, BS Teh, SS Lo, A Muacevic, S Siva

Journal of Urology | LIPPINCOTT WILLIAMS & WILKINS | Published : 2019

DOI: 10.1097/JU.0000000000000111

Abstract

Purpose: Stereotactic ablative radiotherapy is an emerging treatment for renal cell carcinoma. Our study objective was to evaluate this therapy in patients with a solitary kidney, focusing on oncologic and renal function outcomes. Materials and Methods: We pooled individual patient data from 9 IROCK (International Radiosurgery Oncology Consortium for Kidney) institutions in Germany, Australia, the United States of America, Canada and Japan. Median followup was 2.6 years. Baseline characteristics and outcomes were compared between the solitary and bilateral kidney cohorts. Predictors of renal function after stereotactic ablative radiotherapy were assessed by logistic regression modeling. Resu..

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