Sodium Intake, Circulating Microvesicles and Cardiovascular Outcomes in Type 2 Diabetes
Dorothy Liu, Sara Baqar, Lisa L Lincz, Elif Ekinci
CURRENT DIABETES REVIEWS | BENTHAM SCIENCE PUBL LTD | Published : 2019
There is ongoing debate surrounding the complex relationship between dietary sodium intake and cardiovascular morbidity and mortality. The existing literature consists largely of observational studies that have demonstrated positive, negative, U-/J-shaped or unclear associations between sodium intake and cardiovascular outcomes. Our group and others have previously demonstrated an inverse relationship between dietary sodium intake and cardiovascular outcomes in people with type 2 diabetes. Increased activity of the renin-angiotensin-aldosterone system and sympathetic nervous system is postulated to contribute to these paradoxical findings through endothelial dysfunction, a precursor to the d..View full abstract
Awarded by National Heart Foundation Health Professional Scholarship
Prof. Ekinci was supported by a Viertel Clinical Investigatorship, Sir Edward Weary Dunlop Medical Research Foundation grant and RACP fellowship. Dr Baqar was supported by a National Heart Foundation Health Professional Scholarship (100287). The Authors declare that there is no conflict of interest.