Journal article
The blood pressure paradox in acute ischemic stroke
L Hong, X Cheng, L Lin, A Bivard, Y Ling, K Butcher, Q Dong, M Parsons
Annals of Neurology | WILEY | Published : 2019
DOI: 10.1002/ana.25428
Abstract
Objective: To explore the association of poststroke baseline blood pressure with cerebral collateral flow and functional outcome in acute ischemic patients with large vessel occlusion/stenosis. Methods: Patients identified with large vessel occlusion/stenosis with baseline multimodal computed tomography, follow-up imaging, and complete clinical profiles were included. A 90-day modified Rankin Scale of 0–1 was defined as an excellent functional outcome. Cerebral collateral flow was quantified by the volume ratio of tissue within the delay time >3 seconds perfusion lesion with severely delayed contrast transit (delay time >3 seconds/delay time >6 seconds). Results: There were 306 patients incl..
View full abstractGrants
Awarded by National Health and Medical Research Council
Funding Acknowledgements
This study is funded by the National Key R&D Program of China (2017YFC1308201, 2016YFC1300503), National Natural Science Foundation of China (81100861), a grant from the Science and Technical Committee of Shanghai Municipality (124119a8100), and a National Health and Medical Research Council of Australia (1013719).