Journal article

Multicomponent non-pharmacological intervention to prevent delirium for hospitalised people with advanced cancer: Study protocol for a phase II cluster randomised controlled trial

A Hosie, J Phillips, L Lam, S Kochovska, B Noble, M Brassil, SE Kurrle, A Cumming, GA Caplan, R Chye, B Le, EW Ely, PG Lawlor, SH Bush, JM Davis, M Lovell, L Brown, B Fazekas, SL Cheah, L Edwards Show all

BMJ Open | BMJ PUBLISHING GROUP | Published : 2019

Abstract

Introduction Delirium is a significant medical complication for hospitalised patients. Up to one-third of delirium episodes are preventable in older inpatients through non-pharmacological strategies that support essential human needs, such as physical and cognitive activity, sleep, hydration, vision and hearing. We hypothesised that a multicomponent intervention similarly may decrease delirium incidence, and/or its duration and severity, in inpatients with advanced cancer. Prior to a phase III trial, we aimed to determine if a multicomponent non-pharmacological delirium prevention intervention is feasible and acceptable for this specific inpatient group. Methods and analysis The study is a p..

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University of Melbourne Researchers

Grants

Awarded by National Breast Cancer Foundation


Funding Acknowledgements

This work was supported by an Australian National Breast Cancer Foundation (NBCF) 2017 Pilot Study Grant (grant code PS-17-030). The trial sponsor is PaCCSC. PaCCSC supports optimal trial governance through SOPs for electronic data handling, completion of CRFs, monitoring, dissemination, archiving of research materials and record destruction; and trial infrastructure through Trials Management and Scientific Committees.