Journal article
Multicomponent non-pharmacological intervention to prevent delirium for hospitalised people with advanced cancer: Study protocol for a phase II cluster randomised controlled trial
A Hosie, J Phillips, L Lam, S Kochovska, B Noble, M Brassil, SE Kurrle, A Cumming, GA Caplan, R Chye, B Le, EW Ely, PG Lawlor, SH Bush, JM Davis, M Lovell, L Brown, B Fazekas, SL Cheah, L Edwards Show all
BMJ Open | BMJ PUBLISHING GROUP | Published : 2019
Abstract
Introduction Delirium is a significant medical complication for hospitalised patients. Up to one-third of delirium episodes are preventable in older inpatients through non-pharmacological strategies that support essential human needs, such as physical and cognitive activity, sleep, hydration, vision and hearing. We hypothesised that a multicomponent intervention similarly may decrease delirium incidence, and/or its duration and severity, in inpatients with advanced cancer. Prior to a phase III trial, we aimed to determine if a multicomponent non-pharmacological delirium prevention intervention is feasible and acceptable for this specific inpatient group. Methods and analysis The study is a p..
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Awarded by National Breast Cancer Foundation
Funding Acknowledgements
This work was supported by an Australian National Breast Cancer Foundation (NBCF) 2017 Pilot Study Grant (grant code PS-17-030). The trial sponsor is PaCCSC. PaCCSC supports optimal trial governance through SOPs for electronic data handling, completion of CRFs, monitoring, dissemination, archiving of research materials and record destruction; and trial infrastructure through Trials Management and Scientific Committees.