Journal article

Potential Use of Cannabinoids for the Treatment of Pancreatic Cancer

Golnaz Sharafi, Hong He, Mehrdad Nikfarjam

Journal of Pancreatic Cancer | MARY ANN LIEBERT, INC | Published : 2019

Abstract

Background: Cannabinoid extracts may have anticancer properties, which can improve cancer treatment outcomes. The aim of this review is to determine the potentially utility of cannabinoids in the treatment of pancreatic cancer. Methods: A literature review focused on the biological effects of cannabinoids in cancer treatment, with a focus on pancreatic cancer, was conducted. In vitro and in vivo studies that investigated the effects of cannabinoids in pancreatic cancer were identified and potential mechanisms of action were assessed. Results: Cannabinol receptors have been identified in pancreatic cancer with several studies showing in vitro antiproliferative and proapoptotic effects. The ma..

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