6-Phenylpyrimidin-4-ones as Positive Allosteric Modulators at the M-1 mAChR: The Determinants of Allosteric Activity
Manuela Jorg, Emma T van der Westhuizen, Elham Khajehali, Wessel AC Burger, Jonathan M White, Kwok HC Choy, Andrew B Tobin, Patrick M Sexton, Celine Valant, Ben Capuano, Arthur Christopoulos, Peter J Scammells
ACS Chemical Neuroscience | AMER CHEMICAL SOC | Published : 2019
Awarded by Australian Research Council (ARC)
Awarded by National Health and Medicinal Research Council (NHMRC) of Australia
Awarded by Wellcome Trust Collaborative Research Award
Awarded by NHMRC
This research was supported by Discovery grant DP110100687 of the Australian Research Council (ARC), Program grant APP1055134 and Project grant APP1049564 of the National Health and Medicinal Research Council (NHMRC) of Australia, and Wellcome Trust Collaborative Research Award (201529/Z/16/Z). A.C. is a Senior Principal Research Fellow, and P.M.S. a Principal Research Fellow, of the NHMRC. E.T.vdW is an Early Career Researcher of the NHMRC (GNT1013819). C.V. is an ARC Future Fellow.