Journal article

A blinded, three-arm randomised trial assessing joint function and measuring three-dimensional knee joint kinematics in individuals six months after a total knee joint replacement; comparing a medially stabilised design, to standard fixed bearing conventional designs – posterior stabilising and cruciate retaining

Michelle M Dowsey, Marcus Pandy, Tony J Young, Hans Gray, Shangyuanye Guan, Peter F Choong

International Journal of Clinical Trials | Medip Academy

Abstract

Background: No randomised trial exists to assess the relative prosthetic performance of three fixed bearing total knee joint replacement construct designs through clinical functional outcomes and biomechanical gait analysis at six months after the index procedure.Methods: The design of a double blinded, prospective, randomised trial with three parallel patient groups is presented.   Patients reviewed in consultant clinic with radiographic and clinical diagnosis of osteoarthritis of the knee, with the condition deemed severe enough to require a total knee joint replacement (TKJR) are eligible.  Subjects enrolled in the trial are randomised to one of the three TKJR construct designs approximat..

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