Journal article

Human CD8( ) T cell cross-reactivity across influenza A, B and C viruses

Marios Koutsakos, Patricia T Illing, Thi HO Nguyen, Nicole A Mifsud, Jeremy Chase Crawford, Simone Rizzetto, Auda A Eltahla, E Bridie Clemens, Sneha Sant, Brendon Y Chua, Chinn Yi Wong, E Kaitlynn Allen, Don Teng, Pradyot Dash, David F Boyd, Ludivine Grzelak, Weiguang Zeng, Aeron C Hurt, Ian Barr, Steve Rockman Show all

Nature Immunology | NATURE PUBLISHING GROUP | Published : 2019

Grants

Awarded by Australian National Health and Medical Research Council (NHMRC) NHMRC Program Grant


Awarded by NHMRC principal research fellowship


Awarded by NHMRC project grant


Awarded by US National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Department of Health and Human Services


Awarded by NHMRC Peter Doherty fellowship


Awarded by St. Jude Center of Excellence for Influenza Research and Surveillance (NIAID)


Awarded by JDRF Career Development award


Awarded by NHMRC Project



Funding Acknowledgements

HLA-A2.1 transgenic HHD mice were developed by F. Lemonnier (Pasteur Institute). D227K and Q115E MHC-I constructs were developed and provided by L. Wooldridge (Bristol University). The authors acknowledge the provision of instrumentation, training and technical support by the Monash Biomedical Proteomics Facility. We thank all study participants and organ donors. We are grateful to the coordinators of DonateLife Victoria for obtaining organ tissues, and to L. Mariana and C. Kos (St. Vincent's Institute) for their assistance. The Australian National Health and Medical Research Council (NHMRC) NHMRC Program Grant (1071916) to K.K. supported this work. M.K. is a recipient of a Melbourne International research scholarship and Melbourne International fee remission scholarship. S.S. is a recipient of a Victoria India doctoral scholarship and Melbourne International fee remission scholarship, University of Melbourne. K.K. is an NHMRC senior research level B fellow (1102792). J.R. is supported by an ARC laureate fellowship. S.G. is a Monash senior research fellow. F.L. and A.C.C. are NHMRC CDF2 fellows. E.B.C. and A.A.E. are NHMRC Peter Doherty fellows. The Melbourne WHO Collaborating Centre for Reference Research on Influenza is supported by the Australian Government Department of Health. A.W.P. is supported by an NHMRC principal research fellowship (1137739) and an NHMRC project grant (1085018) to A.W.P., T.C.K. and N.A.M. D.T. and D.V. are supported by contract HHSN272201400006C from the US National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Department of Health and Human Services. P.T.I. was supported by a NHMRC Peter Doherty fellowship (1072159). P.G.T. is supported by the St. Jude Center of Excellence for Influenza Research and Surveillance (NIAID contract HHSN27220140006C), R01AI107625, R01AI136514, and American Lebanese Syrian Associated Charities. S.I.M. is supported by a JDRF Career Development award (5-CDA2014210-A-N) and NHMRC Project (GNT 1123586).