Systematic review and consensus definitions for the Standardised Endpoints in Perioperative Medicine (StEP) initiative: infection and sepsis

J Barnes; J Hunter; S Harris; M Shankar-Hari; E Diouf; I Jammer; C Kalkman; AA Klein; T Corcoran; S Dieleman; MPW Grocott; MG Mythen; P Myles; TJ Gan; A Kurz; P Peyton; D Sessler; M Tramèr; A Cyna; GS De Oliveira; C Wu; M Jensen; H Kehlet; M Botti; O Boney; G Haller; M Grocott; T Cook; L Fleisher; M Neuman; D Story; R Gruen; S Bampoe; L Evered; D Scott; B Silbert; D van Dijk; M Chan; H Grocott; R Eckenhoff; L Rasmussen; L Eriksson; S Beattie; D Wijeysundera; G Landoni; K Leslie; B Biccard; S Howell; P Nagele; T Richards; A Lamy; M Lalu; R Pearse; M Mythen; J Canet; A Moller; T Gin; M Schultz; P Pelosi; M Gabreu; E Futier; B Creagh-Brown; A Fowler; T Abbott; A Klein; DJ Cooper; D McIlroy; R Bellomo; A Shaw; J Prowle; K Karkouti; J Billings; D Mazer; M Jayarajah; M Murphy; J Bartoszko; R Sneyd; S Morris; R George; R Moonesinghe; M Shulman; M Lane-Fall; U Nilsson; N Stevenson; W van Klei; L Cabrini; T Miller; N Pace; S Jackson; D Buggy; T Short; B Riedel; V Gottumukkala; B Alkhaffaf; M Johnson

Journal article

Systematic review and consensus definitions for the Standardised Endpoints in Perioperative Medicine (StEP) initiative: infection and sepsis

J Barnes, J Hunter, S Harris, M Shankar-Hari, E Diouf, I Jammer, C Kalkman, AA Klein, T Corcoran, S Dieleman, MPW Grocott, MG Mythen, P Myles, TJ Gan, A Kurz, P Peyton, D Sessler, M Tramèr, A Cyna, GS De Oliveira Show all

British Journal of Anaesthesia | ELSEVIER SCI LTD | Published : 2019

DOI: 10.1016/j.bja.2019.01.009

Abstract

Background: Perioperative infection and sepsis are of fundamental concern to perioperative clinicians. However, standardised endpoints are either poorly defined or not routinely implemented. The Standardised Endpoints in Perioperative Medicine (StEP) initiative was established to derive a set of standardised endpoints for use in perioperative clinical trials. Methods: We undertook a systematic review to identify measures of infection and sepsis used in the perioperative literature. A multi-round Delphi consensus process that included more than 60 clinician researchers was then used to refine a recommended list of outcome measures. Results: A literature search yielded 1857 titles of which 255..

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University of Melbourne Researchers

Grants

Awarded by National Institute of Academic Anaesthesia

Funding Acknowledgements

The Standardized Endpoints for Perioperative Medicine (StEP) Collaborative has been supported by an unrestricted grant from the British Journal of Anaesthesia as well as administrative support from the National Institute of Academic Anaesthesia Health Services Research Centre and the Department of Anaesthesia and Perioperative Medicine, Monash University. M.P.W.G. is a National Institute of Health Research Senior Investigator. M.S.H. is supported by the National Institute for Health Research Clinician Scientist Award (NIHR-CS-2016-16-011). The views expressed in this publication are those of the authors and not necessarily those of the National Health Service, the National Institute for Health Research or the Department of Health.