Journal article

Benefit of Echocardiography in Patients With Staphylococcus aureus Bacteremia at Low Risk of Endocarditis

George S Heriot, Steven YC Tong, Allen C Cheng, Danny Liew

OPEN FORUM INFECTIOUS DISEASES | OXFORD UNIV PRESS INC | Published : 2018

Abstract

Background: The risk of endocarditis among patients with Staphylococcus aureus bacteremia is not uniform, and a number of different scores have been developed to identify patients whose risk is less than 5%. The optimal echocardiography strategy for these patients is uncertain. Methods: We used decision analysis and Monte Carlo simulation using input parameters taken from the existing literature. The model examined patients with S aureus bacteremia whose risk of endocarditis is less than 5%, generally those with nosocomial or healthcare-acquired bacteremia, no intracardiac prosthetic devices, and a brief duration of bacteremia. We examined 6 echocardiography strategies, including the use of ..

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Grants

Awarded by Australian National Health and Medical Research Council Career Development Fellowship


Funding Acknowledgements

This work was funded by the Australian Government Research Training Program and the Monash University Faculty of Medicine, Nursing and Health Sciences (to G.S.H.) and an Australian National Health and Medical Research Council Career Development Fellowship (no. 1065736; to S.Y.C.T.). S.Y.C.T. is the holder of Australian National Health and Medical Research Council grants including for the performance of a randomized controlled trial in the treatment of methicillin-resistant Staphylococcus aureus.