Journal article
Multisite Direct Determination of the Potential for Environmental Contamination of Urine Samples Used for Diagnosis of Sexually Transmitted Infections
Patiyan Andersson, Steven YC Tong, Rachael A Lilliebridge, Nicole C Brenner, Louise M Martin, Emma Spencer, Jennifer Delima, Gurmeet Singh, Frances McCann, Carolyn Hudson, Tracy Johns, Philip M Giffard
JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY | OXFORD UNIV PRESS | Published : 2014
DOI: 10.1093/jpids/pit085
Abstract
BACKGROUND: The detection of a sexually transmitted infection (STI) agent in a urine specimen from a young child is regarded as an indicator of sexual contact. False positives may conceivably arise from the transfer of environmental contaminants in clinic toilet or bathroom facilities into urine specimens. METHODS: The potential for contamination of urine specimens with environmental STI nucleic acid was tested empirically in the male and female toilets or bathrooms at 10 Northern Territory (Australia) clinics, on 7 separate occasions at each. At each of the 140 experiments, environmental contamination with Chlamydia trachomatis, Neisseria gonorrhoeae, and Trichomonas vaginalis nucleic acid ..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
This work was supported by the National Health and Medical Research Council (project grant 1004123; and postdoctoral training fellowship 508829 to S.Y.C.T.); and the Northern Territory (Australia) Research and Innovation Board (Research and Innovation Grant "Urine surrogates in the quality control of Chlamydia diagnosis").