Microsimulation model for the health economic evaluation of osteoporosis interventions: study protocol
Lei Si, John A Eisman, Tania Winzenberg, Kerrie M Sanders, Jacqueline R Center, Tuan V Nguyen, Andrew J Palmer
BMJ OPEN | BMJ PUBLISHING GROUP | Published : 2019
INTRODUCTION: Osteoporosis is a systemic skeletal disease that is characterised by reduced bone strength and increased fracture risk. Osteoporosis-related fractures impose enormous disease and economic burden to the society. Although many treatments and health interventions are proven effective to prevent fractures, health economic evaluation adds evidence to their economic merits. Computer simulation modelling is a useful approach to extrapolate clinical and economic outcomes from clinical trials and it is increasingly used in health economic evaluation. Many osteoporosis health economic models have been developed in the past decades; however, they are limited to academic use and there are ..View full abstract
Awarded by National Health and Medical Research Council (NHMRC)
Awarded by NHMRC Early Career Fellowship
This study is supported by a National Health and Medical Research Council (NHMRC) project grant (APP1127827). LS is a recipient of the NHMRC Early Career Fellowship (GNT1139826). The contents of this publication is solely the responsibility of the authors and does not necessarily represent the official views of the NHMRC.