Journal article
Cost-effectiveness of different interferon beta products for relapsing-remitting and secondary progressive multiple sclerosis: Decision analysis based on long-term clinical data and switchable treatments
S Nikfar, A Kebriaeezadeh, R Dinarvand, M Abdollahi, MA Sahraian, D Henry, A Akbari Sari
Daru Journal of Pharmaceutical Sciences | BIOMED CENTRAL LTD | Published : 2013
Open access
Abstract
Background: Multiple sclerosis (MS) is a highly debilitating immune mediated disorder and the second most common cause of neurological disability in young and middle-aged adults. Iran is amongst high MS prevalence countries (50/100,000). Economic burden of MS is a topic of important deliberation in economic evaluations study. Therefore determining of cost-effectiveness interferon beta (INF β) and their copied biopharmaceuticals (CBPs) and biosimilars products is significant issue for assessment of affordability in Lower-middle-income countries (LMICs). Methods. A literature-based Markov model was developed to assess the cost-effectiveness of three INF βs products compared with placebo for ma..
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Funding Acknowledgements
Authors thank Iranian Society of multiple sclerosis for their kind assistance in collecting information of patients. This paper is the outcome of a PhD thesis of the first author and was supported by Faculty of Pharmacy, Tehran University of Medical Sciences.