Journal article

Platelet-rich-plasmapheresis for minimising peri-operative allogeneic blood transfusion

Paul A Carless, Fraser D Rubens, Danielle M Anthony, Dianne O'Connell, David A Henry

COCHRANE DATABASE OF SYSTEMATIC REVIEWS | WILEY | Published : 2011

Abstract

BACKGROUND: Concerns regarding the safety of transfused blood have generated considerable enthusiasm for the use of technologies intended to reduce the use of allogeneic blood (blood from an unrelated donor). Platelet-rich plasmapheresis (PRP) offers an alternative approach to blood conservation. OBJECTIVES: To examine the evidence for the efficacy of PRP in reducing peri-operative allogeneic red blood cell (RBC) transfusion, and the evidence for any effect on clinical outcomes such as mortality and re-operation rates. SEARCH STRATEGY: We identified studies by searching MEDLINE (1950 to 2009), EMBASE (1980 to 2009), The Cochrane Library (Issue 1, 2009), the Internet (to March 2009) and the r..

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