Platelet-rich-plasmapheresis for minimising peri-operative allogeneic blood transfusion
Paul A Carless, Fraser D Rubens, Danielle M Anthony, Dianne O'Connell, David A Henry
COCHRANE DATABASE OF SYSTEMATIC REVIEWS | WILEY | Published : 2011
BACKGROUND: Concerns regarding the safety of transfused blood have generated considerable enthusiasm for the use of technologies intended to reduce the use of allogeneic blood (blood from an unrelated donor). Platelet-rich plasmapheresis (PRP) offers an alternative approach to blood conservation. OBJECTIVES: To examine the evidence for the efficacy of PRP in reducing peri-operative allogeneic red blood cell (RBC) transfusion, and the evidence for any effect on clinical outcomes such as mortality and re-operation rates. SEARCH STRATEGY: We identified studies by searching MEDLINE (1950 to 2009), EMBASE (1980 to 2009), The Cochrane Library (Issue 1, 2009), the Internet (to March 2009) and the r..View full abstract
External sourcesNational Health and Medical Research Council of Australia, Australia.