Journal article

Tricyclic drugs for depression in children and adolescents

P Hazell, D O'Connell, D Heathcote, D Henry

Praxis | WILEY | Published : 2001

Abstract

BACKGROUND: There is a need to identify effective and safe treatments for depression in children and adolescents. While tricyclic drugs are effective in treating depression in adults, individual studies involving children and adolescents have been equivocal. Prescribing of tricyclic drugs for depression in children and adolescents is now uncommon, but an accurate estimate of their efficacy is helpful as a comparator for other drug treatments for depression in this age group. This is an update of a Cochrane review first published in 2000 and updated in 2002, 2006 and 2010. OBJECTIVES: To assess the effects of tricyclic drugs compared with placebo for depression in children and adolescents and..

View full abstract

University of Melbourne Researchers