Journal article

Decreased regional cortical thickness and thinning rate are associated with inattention symptoms in healthy children.

Simon Ducharme, James J Hudziak, Kelly N Botteron, Matthew D Albaugh, Tuong-Vi Nguyen, Sherif Karama, Alan C Evans, undefined Brain Development Cooperative Group

J Am Acad Child Adolesc Psychiatry | Published : 2012


OBJECTIVE: Children with attention-deficit/hyperactivity disorder (ADHD) have delayed cortical maturation, evidenced by regionally specific slower cortical thinning. However, the relationship between cortical maturation and attention capacities in typically developing children is unknown. This study examines cortical thickness correlates of inattention symptoms in a large sample of healthy children. METHOD: Data from 357 healthy subjects (6.0-18.4 years of age) were obtained from the NIH MRI Study of Normal Brain Development. In cross-sectional analysis (first visit, n = 257), Child Behavior Checklist Attention Problems (AP) scores were linearly regressed against cortical thickness, controll..

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