Journal article

Exercise serum increases GLUT4 in human adipocytes

M Flores-Opazo, A Raajendiran, MJ Watt, M Hargreaves

Experimental Physiology | WILEY | Published : 2019

Abstract

New Findings: What is the central question of this study? Do circulating factors mediate exercise-induced effects on adipose tissue GLUT4 expression? What is the main finding and its importance? Serum (10%) obtained from human volunteers immediately after a single exercise bout increased GLUT4 protein levels in human adipocytes in culture. This result suggests that circulating factors might mediate the effects of exercise on adipose tissue GLUT4 and prompts further effort to identify the specific factor(s) and tissue(s) of origin. Abstract: In this study, we tested the hypothesis that circulating factors generated during exercise increase adipose tissue GLUT4 expression. Serum was obtained f..

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University of Melbourne Researchers

Grants

Awarded by McMaster University


Funding Acknowledgements

This study was supported by the Diabetes Australia Research Program (Y14G-HARM1). M.F.-O. was supported by the Becas Chile scholarship program of National Commission for Scientific and Technological Research Chile (CONYCIT).