Effects of ABO matching of platelet transfusions in critically III children

ME Nellis; R Goel; O Karam; MM Cushing; PJ Davis; ME Steiner; M Tucci; SJ Stanworth; PC Spinella; W Butt; C Delzoppo; S Erickson; E Croston; S Barr; E Cavazzoni; A de Jaeger; ME French; M Ropars; L Clayton; S Murthy; G Krahn; D Qu; Y Hui; M Johansen; AMB Jensen; IL Jarnvig; D Strange; M Jayashree; M Reddy; J Sankar; UV Kumar; R Lodha; RK Lerner; G Paret; O Schiller; E Shostak; O Dagan; Y Cavari; F Chiusolo; A Cillis; A Camporesi; M Kneyber; SCD Otter; E Van Hemeldonck; J Beca; C Sherring; M Rea; C Abadesso; M Moniz; S Alshehr; J Lopez-Herce; I Ortiz; M Garcia; I Jordan; JCF Gonzalez; A Perez-Ferrer; A Pascual-Albitre; S Grazioli; C Doell; I Curio; A Jones; MJ Peters; J Lillie; A Aramburo; M Shabana; P Ramachandran; H Sampaio; K Sadasivam; NJ Prince; HK Kanthimathinathan; RG Branco; KL Sykes; C Mel-Lish; A Sarfatti; J Weitz; RC Sanders; G Hefley; RSP Morzov; B Markovitz; A Ratiu; A Sapru; AS Cowl; E Vincent; S Faustino; S Mahadevaiah; F Beltramo; AS Jeyapalan; MK Cousins; C Stone; J Fortenberry; NP Pinto; C Rodgers; A Kniola; M Porter; E Owen; K Lee; LJ Thomas; MM Bembea

Journal article

Effects of ABO matching of platelet transfusions in critically III children

ME Nellis, R Goel, O Karam, MM Cushing, PJ Davis, ME Steiner, M Tucci, SJ Stanworth, PC Spinella, W Butt, C Delzoppo, S Erickson, E Croston, S Barr, E Cavazzoni, A de Jaeger, ME French, M Ropars, L Clayton, S Murthy Show all

Pediatric Critical Care Medicine | LIPPINCOTT WILLIAMS & WILKINS | Published : 2019

DOI: 10.1097/PCC.0000000000001779

Abstract

Objectives: To determine if transfusing ABO compatible platelets has a greater effect on incremental change in platelet count as compared to ABO incompatible platelets in critically ill children. Design: Secondary analysis of a prospective, observational study. Transfusions were classified as either ABO compatible, major incompatibility, or minor incompatibility. The primary outcome was the incremental change in platelet count. Transfusion reactions were analyzed as a secondary outcome. Setting: Eighty-two PICUs in 16 countries. Patients: Children (3 d to 16 yr old) were enrolled if they received a platelet transfusion during one of the predefined screening weeks. Interventions: None. Measur..

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University of Melbourne Researchers

Warwick Butt Author

Grants

Awarded by National Center for Advancing Translational Sciences

Funding Acknowledgements

Supported, in part, by funds from the Clinical Translational Science Center, National Center for Advancing Translational Sciences grant number UL1-TR000457.