Journal article

Maternal fetal programming of birthweight among Australian Aboriginal infants: a population-based data linkage study

Alison J Gibberd, Judy M Simpson, Bridgette J McNamara, Sandra J Eades

LANCET GLOBAL HEALTH | ELSEVIER SCI LTD | Published : 2019

Abstract

BACKGROUND: Low birthweight, which is common among Australian Aboriginal infants, has been found to persist across generations because of shared genetic and environmental factors and possibly fetal programming. Fetal programming refers to the response of a fetus to hostile uterine conditions with lifelong effects and possibly, in turn, providing a poorer uterine environment for future offspring. Fetal programming might have a greater effect in populations that have undergone rapid lifestyle transitions-for example, Indigenous populations. Disentangling causal effects is difficult, but family-based approaches could provide insights. We explored whether poor maternal fetal growth caused low bi..

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