Maternal fetal programming of birthweight among Australian Aboriginal infants: a population-based data linkage study
Alison J Gibberd, Judy M Simpson, Bridgette J McNamara, Sandra J Eades
LANCET GLOBAL HEALTH | ELSEVIER SCI LTD | Published : 2019
BACKGROUND: Low birthweight, which is common among Australian Aboriginal infants, has been found to persist across generations because of shared genetic and environmental factors and possibly fetal programming. Fetal programming refers to the response of a fetus to hostile uterine conditions with lifelong effects and possibly, in turn, providing a poorer uterine environment for future offspring. Fetal programming might have a greater effect in populations that have undergone rapid lifestyle transitions-for example, Indigenous populations. Disentangling causal effects is difficult, but family-based approaches could provide insights. We explored whether poor maternal fetal growth caused low bi..View full abstract
National Health and Medical Research Council of Australia and Bellberry Ltd.