F-18-FLUORODEOXYGLUCOSE POSITRON EMISSION TOMOGRAPHY/COMPUTED TOMOGRAPHY BASED RADIOTHERAPY TARGET VOLUME DEFINITION IN NON-SMALL-CELL LUNG CANCER: DELINEATION BY RADIATION ONCOLOGISTS VS. JOINT OUTLINING WITH A PET RADIOLOGIST?
Gerard G Hanna, Kathryn J Carson, Tom Lynch, Jonathan McAleese, Vivian P Cosgrove, Ruth L Eakin, David P Stewart, Ashraf Zatari, Joe M O'Sullivan, Alan R Hounsell
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | ELSEVIER SCIENCE INC | Published : 2010
PURPOSE: (18)F-Fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) has benefits in target volume (TV) definition in radiotherapy treatment planning (RTP) for non-small-cell lung cancer (NSCLC); however, an optimal protocol for TV delineation has not been determined. We investigate volumetric and positional variation in gross tumor volume (GTV) delineation using a planning PET/CT among three radiation oncologists and a PET radiologist. METHODS AND MATERIALS: RTP PET/CT scans were performed on 28 NSCLC patients (Stage IA-IIIB) of which 14 patients received prior induction chemotherapy. Three radiation oncologists and one PET radiologist working with a fourth radiation ..View full abstract
Supported by The Research and Development Office, Northern Ireland Health and Social Services.