Journal article

Conventional 3D staging PET/CT in CT simulation for lung cancer: impact of rigid and deformable target volume alignments for radiotherapy treatment planning

GG Hanna, JR van Sornsen de Koste, KJ Carson, JM O'Sullivan, AR Hounsell, S Senan

BRITISH JOURNAL OF RADIOLOGY | BRITISH INST RADIOLOGY | Published : 2011

Abstract

OBJECTIVE: Positron emission tomography (PET)/CT scans can improve target definition in radiotherapy for non-small cell lung cancer (NSCLC). As staging PET/CT scans are increasingly available, we evaluated different methods for co-registration of staging PET/CT data to radiotherapy simulation (RTP) scans. METHODS: 10 patients underwent staging PET/CT followed by RTP PET/CT. On both scans, gross tumour volumes (GTVs) were delineated using CT (GTV(CT)) and PET display settings. Four PET-based contours (manual delineation, two threshold methods and a source-to-background ratio method) were delineated. The CT component of the staging scan was co-registered using both rigid and deformable techniq..

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Grants

Funding Acknowledgements

Funding for Dr Hanna was kindly provided by the Research and Development Office, Northern Ireland Health and Social Services. Dr Hanna also received funding from the Keith Durrant Travelling Fellowship, Royal College of Radiologists, London, towards this work. The VU University Medical Centre has a research collaboration with Velocity Medical Solutions, Atlanta, GA.