Elevated ubiquitinated proteins in brain and blood of individuals with schizophrenia
Chad A Bousman, Sandra Luza, Serafino G Mancuso, Dali Kang, Carlos M Opazo, Md Shaki Mostaid, Vanessa Cropley, Patrick McGorry, Cynthia Shannon Weickert, Christos Pantelis, Ashley I Bush, Ian P Everall
Scientific Reports | NATURE RESEARCH | Published : 2019
Awarded by National Health and Medical Research Council of Australia
Awarded by National Institute of Alcohol Abuse and Alcoholism (NIH (NIAAA))
Awarded by National Health and Medical Research Council of Australia (NHMRC) Career Development Fellowship
Awarded by NHMRC Senior Principal Research Fellowship
The authors acknowledge the financial support of the CRC for Mental Health. The Cooperative Research Centre (CRC) programme is an Australian Government Initiative. The authors also wish to acknowledge the CRC Scientific Advisory Committee, in addition to the contributions of study participants, clinicians at recruitment services, staff at the Murdoch Children's Research Institute, staff at the Australian Imaging, Biomarkers and Lifestyle Flagship Study of Aging, and research staff at the Melbourne Neuropsychiatry Centre, including coordinators Phassouliotis, C., Merritt, A., and research assistants, Burnside, A., Cross, H., Gale, S., and Tahtalian, S. Participants for this study were sourced, in part, through the Australian Schizophrenia Research Bank (ASRB), which is supported by the National Health and Medical Research Council of Australia (Enabling Grant No. 386500), the Pratt Foundation, Ramsay Health Care, the Viertel Charitable Foundation and the Schizophrenia Research Institute. Postmortem tissues were received from the New South Wales Tissue Resource Center at the University of Sydney, which is supported by the National Health and Medical Research Council of Australia, Schizophrenia Research Institute, National Institute of Alcohol Abuse and Alcoholism (NIH (NIAAA) R24AA012725). C.A.B. was supported by a National Health and Medical Research Council of Australia (NHMRC) Career Development Fellowship (1127700). C.P. was supported by NHMRC Senior Principal Research Fellowship (628386 & 1105825). A.I.B. was supported by NHMRC Senior Principal Research Fellowship (1103703). None of the funding sources played any role in the study design; collection, analysis or interpretation of data; in the writing of the report; or in the decision to submit the paper for publication. We thank the Chief Investigators and ASRB Manager: Carr, V., Schall, U., Scott, R., Jablensky, A., Mowry, B., Michie, P., Catts, S., Henskens, F., Pantelis, C., Loughland, C. We acknowledge the help of Jason Bridge for ASRB database queries.