Bipolar disorder and bone health: A systematic review

Vinoomika Chandrasekaran; Sharon L Brennan-Olsen; Amanda L Stuart; Julie A Pasco; Michael Berk; Jason M Hodge; Lana J Williams

Journal article

Bipolar disorder and bone health: A systematic review

Vinoomika Chandrasekaran, Sharon L Brennan-Olsen, Amanda L Stuart, Julie A Pasco, Michael Berk, Jason M Hodge, Lana J Williams

JOURNAL OF AFFECTIVE DISORDERS | ELSEVIER | Published : 2019

DOI: 10.1016/j.jad.2019.02.013

Abstract

BACKGROUND: Bipolar disorder is a chronic, episodic mental illness, affecting around 2.4% of the population worldwide. Psychological and/or physiological comorbidities are a common consequence, and osteoporosis is one such possible comorbidity. Thus, this systematic review aimed to collate, evaluate, and discuss the literature examining the link between bipolar disorder and bone health. METHODS: We conducted an e-search of PubMed/OVID/MEDLINE, PsychINFO and CINAHL to identify studies that investigated associations between bipolar disorder and bone in adults aged ≥18. Two reviewers determined eligibility according to pre-determined criteria, and methodological quality was assessed using a pre..

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University of Melbourne Researchers

Jason Hodge Author

Julie Pasco Author

Michael Berk Author Psychiatry

Sharon Brennan-Olsen Author

Related Projects (1)

MULTIDISCIPLINARY TRANSLATIONAL RESEARCH TO ADDRESS SOCIAL DISPARITIES IN OSTEOPOROSIS: UNDERSTANDING THE SOCIAL CONTEXT OF BIOLOGICAL MECHANISMS

Osteoporosis (OP) prevalence is greater for disadvantaged groups, as are less healthy lifestyles. Whilst reasons for this social gradient of..

Grants

Awarded by National Health and Medical Research Council (NHMRC, of Australia)

Awarded by NHMRC Career Development Fellowship

Awarded by NHMRC Senior Principal Research Fellowship

Funding Acknowledgements

The study is supported by the National Health and Medical Research Council (NHMRC, of Australia) (GNT1104438). V.C. is supported by a Deakin University Postgraduate Research Scholarship, S.L.B-O and L.J.W. are each supported by a NHMRC Career Development Fellowship (GNT1107510, and GNT1064272, respectively), and M.B. is supported by a NHMRC Senior Principal Research Fellowship (GNT1059660).