Thiol-Cyanobenzothiazole Ligation for the Efficient Preparation of Peptide-PNA Conjugates

Nitin A Patil; John A Karas; Bradley J Turner; Fazel Shabanpoor

Journal article

Thiol-Cyanobenzothiazole Ligation for the Efficient Preparation of Peptide-PNA Conjugates

Nitin A Patil, John A Karas, Bradley J Turner, Fazel Shabanpoor

Bioconjugate Chemistry | AMER CHEMICAL SOC | Published : 2019

DOI: 10.1021/acs.bioconjchem.8b00908

University of Melbourne Researchers

John Karas Author Chemistry

Fazel Shabanpoor Author Florey Department of Neuroscience and Mental Health

Bradley Turner Author Florey Department of Neuroscience and Mental Health

Related Projects (1)

SMN IMMUNOGENE THERAPY FOR MOTOR NEURON DISORDERS

We have designed novel gene therapy agents to treat MND. This therapeutic approach uniquely combines gene therapy agents with antibodies whi..

Grants

Awarded by National Health and Medical Research Council

Awarded by NHMRC-ARC Dementia Research Leadership Fellowship

Funding Acknowledgements

This work was supported by National Health and Medical Research Council (Project Grants 1138033 to F.S. and B.J.T. and 1104299 to B.J.T.) and Stafford Fox Medical Research Foundation. B.J.T. is a recipient of NHMRC-ARC Dementia Research Leadership Fellowship (1137024). We wish to thank Prof. Jian Li for providing access to LCMS and Prof. John D. Wade for his critical review of the manuscript.