Journal article

Implementation of a practical and effective pilot intervention against transmission of Taenia solium by pigs in the Banke district of Nepal

Ishab Poudel, Keshav Sah, Suyog Subedi, Dinesh Kumar Singh, Peetambar Kushwaha, Angela Colston, Charles G Gauci, Meritxell Donadeu, Marshall W Lightowlers

PLoS Neglected Tropical Diseases | Public Library of Science | Published : 2019


Taenia solium is a zoonotic cestode parasite which causes human neurocysticercosis. Pigs transmit the parasite by acting as the intermediate host. An intervention was implemented to control transmission of T. solium by pigs in Dalit communities of Banke District, Nepal. Every 3 months, pigs were vaccinated with the TSOL18 recombinant vaccine (Cysvax, IIL, India)) and, at the same time, given an oral treatment with 30mg/kg oxfendazole (Paranthic 10% MCI, Morocco). The prevalence of porcine cysticercosis was determined in both an intervention area as well as a similar no intervention control area, among randomly selected, slaughter-age pigs. Post mortem assessments were undertaken both at the ..

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Awarded by Bill & Melinda Gates Foundation

Awarded by UK Government

Awarded by Australian National Health and Medical Research Council

Funding Acknowledgements

This project funded in part by the Bill & Melinda Gates Foundation (OPP1009497; GALVmed [AC]) the UK Government (Component Code 203188-101; GALVmed [AC]). Funding is acknowledged from the Australian National Health and Medical Research Council grant GTN1105448 (MWL) ( funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.