Implementation of a practical and effective pilot intervention against transmission of Taenia solium by pigs in the Banke district of Nepal
Ishab Poudel, Keshav Sah, Suyog Subedi, Dinesh Kumar Singh, Peetambar Kushwaha, Angela Colston, Charles G Gauci, Meritxell Donadeu, Marshall W Lightowlers
PLOS Neglected Tropical Diseases | Public Library of Science | Published : 2019
Taenia solium is a zoonotic cestode parasite which causes human neurocysticercosis. Pigs transmit the parasite by acting as the intermediate host. An intervention was implemented to control transmission of T. solium by pigs in Dalit communities of Banke District, Nepal. Every 3 months, pigs were vaccinated with the TSOL18 recombinant vaccine (Cysvax, IIL, India)) and, at the same time, given an oral treatment with 30mg/kg oxfendazole (Paranthic 10% MCI, Morocco). The prevalence of porcine cysticercosis was determined in both an intervention area as well as a similar no intervention control area, among randomly selected, slaughter-age pigs. Post mortem assessments were undertaken both at the ..View full abstract
Awarded by Bill & Melinda Gates Foundation
Awarded by UK Government
Awarded by Australian National Health and Medical Research Council
This project funded in part by the Bill & Melinda Gates Foundation (OPP1009497; GALVmed [AC]) https://www.gatesfoundation.org/and the UK Government (Component Code 203188-101 https://www.gov.uk/government/organisations/department-for-international-development; GALVmed [AC]). Funding is acknowledged from the Australian National Health and Medical Research Council grant GTN1105448 (MWL) (https://www.nhmrc.gov.au/).The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.