Effect of morning exercise with or without breaks in prolonged sitting on blood pressure in older overweight/obese adults: Evidence for sex differences

MJ Wheeler; DW Dunstan; KA Ellis; E Cerin; S Phillips; G Lambert; LH Naylor; PC Dempsey; BA Kingwell; DJ Green

Journal article

Effect of morning exercise with or without breaks in prolonged sitting on blood pressure in older overweight/obese adults: Evidence for sex differences

MJ Wheeler, DW Dunstan, KA Ellis, E Cerin, S Phillips, G Lambert, LH Naylor, PC Dempsey, BA Kingwell, DJ Green

Hypertension | LIPPINCOTT WILLIAMS & WILKINS | Published : 2019

DOI: 10.1161/HYPERTENSIONAHA.118.12373

Abstract

Both exercise and breaks in prolonged sitting can reduce blood pressure (BP) in older overweight/obese adults. We investigated whether there is an additive hypotensive effect when exercise is combined with subsequent breaks in sitting. Sex differences and changes in plasma catecholamines as a potential candidate mechanism underlying BP responses were also examined. Sedentary older adults (n=67; 67±7 years; 31.2±4.1 kg/m2) completed 3 conditions in random order-sitting (SIT): Uninterrupted sitting (8 hours, control); exercise+sitting (EX+SIT): Sitting (1 hour), moderate-intensity walking (30 minutes), uninterrupted sitting (6.5 hours); exercise+breaks (EX+BR): Sitting (1 hour), moderate-inten..

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University of Melbourne Researchers

Michael Wheeler Author

Kathryn Ellis Author

Bronwyn Kingwell Author

Grants

Awarded by Abbott Laboratories

Funding Acknowledgements

This work was funded by a project grant from the National Health and Medical Research Council of Australia (NHMRC 1062338) and supported in part by the Victorian Government's Operational Infrastructure Support Program. M.J. Wheeler is supported by the University of Western Australia and the Baker Heart and Diabetes Institute. P.C. Dempsey is supported by an NHMRC Fellowship (NHMRC APP1142685). D.W. Dunstan is supported by an NHMRC Senior Research Fellowship (NHMRC APP1078360). E. Cerin is supported by an Australian Research Council Future Fellowship (ARC FT140100085). G. Lambert is supported by an NHMRC Senior Research Fellowship (APP1042492). The laboratory of G. Lambert has recently received research funding from Medtronic, Abbott (formerly Solvay) Pharmaceuticals, Servier Australia, and Allergan. G. Lambert has acted as a consultant for Medtronic. D.J. Green is supported an NHMRC Principal Research Fellowship (APP1080914).