Journal article

Modern technology-derived normative values for cerebral tissue oxygen saturation in adults

Christopher T Eyeington, Paolo Ancona, Eduardo A Osawa, Salvatore L Cutuli, Glenn M Eastwood, Rinaldo Bellomo

Anaesthesia and Intensive Care | SAGE PUBLICATIONS LTD | Published : 2019


Modern near-infrared spectroscopy technology is increasingly adopted to measure cerebral tissue oxygen saturation. However, the normal range of cerebral tissue oxygen saturation in adults with such technology is unknown. We sought to measure cerebral tissue oxygen saturation in healthy volunteers using the novel O3 Regional Oximetry® device (Masimo Corporation, Irvine, CA, USA) and assess its relationship with key physical and haemodynamic characteristics. For ≥5 minutes, we continuously recorded cerebral tissue oxygen saturation, pulse oximetry, cardiac index and mean arterial pressure. We assessed for differences in cerebral tissue oxygen saturation between hemispheres, sex, skin type, com..

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University of Melbourne Researchers


Funding Acknowledgements

The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This study was supported by an unrestricted educational grant from the Austin Hospital Anaesthesia and Intensive Care Trust Fund. None of the authors or the institutions they work for have or are expected to receive any financial or other incentives from Masimo Corporation or Edwards Lifesciences. Neither Masimo Corporation nor Edwards Lifesciences were not involved in any stage of the study design, implementation, data analysis or manuscript preparation.