Journal article

White Matter Biomarkers Associated with Motor Change in Individuals with Stroke: A Continuous Theta Burst Stimulation Study

KP Wadden, S Peters, MR Borich, JL Neva, KS Hayward, CS Mang, NJ Snow, KE Brown, TS Woodward, SK Meehan, LA Boyd

NEURAL PLASTICITY | HINDAWI LTD | Published : 2019

Abstract

Continuous theta burst stimulation (cTBS) is a form of noninvasive repetitive brain stimulation that, when delivered over the contralesional hemisphere, can influence the excitability of the ipsilesional hemisphere in individuals with stroke. cTBS applied prior to skilled motor practice interventions may augment motor learning; however, there is a high degree of variability in individual response to this intervention. The main objective of the present study was to assess white matter biomarkers of response to cTBS paired with skilled motor practice in individuals with chronic stroke. We tested the effects of stimulation of the contralesional hemisphere at the site of the primary motor cortex..

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University of Melbourne Researchers

Grants

Awarded by Canadian Institutes for Health Research (CIHR)


Awarded by National Health and Medical Research Council of Australia


Awarded by Michael Smith Foundation for Health Research, British Columbia, Canada


Funding Acknowledgements

This study was funded by the Canadian Institutes for Health Research (CIHR) Grant (#MOP-106651). KSH was supported by the Michael Smith Foundation for Health Research, British Columbia, Canada (15980) and National Health and Medical Research Council of Australia (1088 449). KPW and KEB were supported by the Natural Sciences and Engineering Research Council (NSERC). JLN was supported by CIHR and the Michael Smith Foundation for Health Research.