Effects of the antibiotic component on in-vitro bacterial killing, physico-chemical properties, aerosolization and dissolution of a ternary-combinational inhalation powder formulation of antibiotics for pan-drug resistant Gram-negative lung infections
Sharad Mangal, Jiayang Huang, Nivedita Shetty, Heejun Park, Yu-Wei Lin, Heidi H Yu, Dmitry Zemlyanov, Tony Velkov, Jian Li, Qi Tony Zhou
International Journal of Pharmaceutics | ELSEVIER SCIENCE BV | Published : 2019
Awarded by National Institute of Allergy and Infectious Diseases of the National Institutes of Health
Awarded by NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Research reported in this publication was supported by the National Institute of Allergy and Infectious Diseases of the National Institutes of Health under Award Number R01AI132681. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. Qi (Tony) Zhou is partically supported by the Ralph W. and Grace M. Showalter Research Trust Award. Jiayang Huang was supported by Purdue College of Pharmacy Dean's Undergraduate Research Fellowship. Jian Li is an Australian NHMRC Research Fellow and Tony Velkov is an NHMRC Career Development Industrial Fellow. Kind donations of RS01 DPI device from Plastiape S.p.A. and HPMC capsules from Qualicaps, Inc are acknowledged.