Secreted cellular prion protein binds doxorubicin and correlates with anthracycline resistance in breast cancer
Adrian P Wiegmans, Jodi M Saunus, Sunyoung Ham, Richard Lobb, Jamie R Kutasovic, Andrew J Dalley, Mariska Miranda, Caroline Atkinson, Simote T Foliaki, Kaltin Ferguson, Colleen Niland, Cameron N Johnstone, Victoria Lewis, Steven J Collins, Sunil R Lakhani, Fares Al-Ejeh, Andreas Moller
JCI Insight | AMER SOC CLINICAL INVESTIGATION INC | Published : 2019
Awarded by Australian National Health & Medical Research Council
We would like to thank Parmjit Jat, Iryna Benilova, and Simon Mead (UCL Institute of Prion Diseases) for critical review and feedback on this manuscript. We thank Jason Lee, QIMR Berghofer Medical Research Institute, for his help with data analysis, revision, and formatting. We also acknowledge the Brisbane Breast Bank for clinical samples for IHC and ELISA studies. This study makes use of data generated by the Molecular Taxonomy of Breast Cancer International Consortium (Metabric). This study was supported by funding from Australian National Health & Medical Research Council project grants (APP1068510 to AM and APP1113867 and APP1017028 to SRL) and the Practitioner Fellowship (APP1105784 to SJC).