Salvage Treatment and Survival for Relapsed Follicular Lymphoma Following Primary Radiation Therapy: A Collaborative Study on Behalf of ILROG

MS Binkley; JL Brady; C Hajj; M Chelius; K Chau; A Balogh; M Levis; AR Filippi; M Jones; S Ahmed; M MacManus; A Wirth; M Oguchi; AK Vistisen; TY Andraos; AK Ng; BMP Aleman; SH Choi; YM Kirova; S Hardy; G Reinartz; HT Eich; SV Bratman; LS Constine; CO Suh; B Dabaja; TC El-Galaly; DC Hodgson; U Ricardi; J Yahalom; NG Mikhaeel; RT Hoppe

Journal article

Salvage Treatment and Survival for Relapsed Follicular Lymphoma Following Primary Radiation Therapy: A Collaborative Study on Behalf of ILROG

MS Binkley, JL Brady, C Hajj, M Chelius, K Chau, A Balogh, M Levis, AR Filippi, M Jones, S Ahmed, M MacManus, A Wirth, M Oguchi, AK Vistisen, TY Andraos, AK Ng, BMP Aleman, SH Choi, YM Kirova, S Hardy Show all

International Journal of Radiation Oncology Biology Physics | ELSEVIER SCIENCE INC | Published : 2019

DOI: 10.1016/j.ijrobp.2019.03.004

Abstract

Purpose: We previously reported that ∼30% of patients with localized follicular lymphoma (FL)staged by 18F-fluorodeoxyglucose positron emission tomography-computed tomography receiving primary radiation therapy (RT)will relapse within 5 years. We sought to report outcomes for those who relapsed. Methods and Materials: We conducted a multicenter, retrospective study of patients aged ≥18 years who received RT ≥ 24 Gy for stage I to II, grade 1 to 3A FL, staged with 18F-fluorodeoxyglucose (18F-FDG)positron emission tomography-computed tomography. Observation was defined as >6 months without treatment from relapse. Overall survival (OS)and freedom from progression (FFP)were estimated with Kaplan..

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