The relationship between hormone therapy use at the time of diagnosis of breast cancer and tumor characteristics.
Mary Panjari, Robin Bell, Marijana Lijovic, Maria La China, Max Schwarz, Pamela Fradkin, Jo Bradbury, Helen Farrugia, Susan R Davis
Hormones and Cancer | Published : 2010
Exposure to postmenopausal hormone therapy (HT) may affect the stage, histological type, and hormone receptor (HR) status of invasive breast cancer at the time of diagnosis. One thousand six hundred eighty-four women with newly diagnosed first invasive breast cancer were recruited to the "MBF Foundation Health and Wellbeing after Breast Cancer Study." Women using systemic HT estrogen (E) or E combined with progesterone (P) at the time of diagnosis of breast cancer were compared with those not using HT. Breast cancer tumor data were obtained from the Victorian Cancer Registry. Regression analysis was used to determine the associations between HT use or not at the time of diagnosis and tumor h..View full abstract