Journal article

The spread of resistance to imidacloprid is restricted by thermotolerance in natural populations of Drosophila melanogaster

Alexandre Fournier-Level, Robert T Good, Stephen A Wilcox, Rahul Rane, Michelle Schiffer, Wei Chen, Paul Battlay, Trent Perry, Philip Batterham, Ary A Hoffmann, Charles Robin

NATURE ECOLOGY & EVOLUTION | NATURE PUBLISHING GROUP | Published : 2019

Abstract

Imidacloprid, the world's most used insecticide, has caused considerable controversy due to harmful effects on non-pest species and increasing evidence showing that insecticides have become the primary selective force in many insect species. The genetic response to insecticides is heterogeneous across populations and environments, leading to more complex patterns of genetic variation than previously thought. This motivated the investigation of imidacloprid resistance at different temperatures in natural populations of Drosophila melanogaster originating from four climate extremes replicated across two continents. Population and quantitative genomic analysis, supported by functional tests, ha..

View full abstract

Grants

Awarded by Human Frontier in Sciences Long-Term fellowship


Funding Acknowledgements

We thank D. Begun, S. Myles and C. Hart for sharing their laboratory facilities, P. Griffin for fly collection, and K. Charles at Foursights Wines, D. Herbert at Herbert Vineyard, P. Dixon at the Henty Estate, J. Leahy at Becker's Vineyard, J. Seago at Ponchartrain Vineyard and Landry Vineyards for providing access to their estates. This work was supported by the Human Frontier in Sciences Long-Term fellowship no. LT000907/2012-L awarded to A.F.L.