Journal article

Review: Using diffusion-weighted magnetic resonance imaging techniques to explore the microstructure and connectivity of subcortical white matter tracts in the human auditory system

Julien Zanin, Thijs Dhollander, Shawna Farquharson, Gary Rance, Alan Connelly, Bryony A Nayagam



Since its inception 30 years ago, diffusion-weighted magnetic resonance imaging (dMRI) has advanced to become a common component of routine clinical MRI examinations. Diffusion-weighted magnetic resonance offers a way to measure anisotropic diffusion in-vivo, which has led to the development of techniques capable of characterising the orientation of diffusion within living tissue. These modelling techniques can be used to investigate the microstructure and connectivity of white matter tracts within the human brain. Such techniques have been used to study many neural networks within the human body. There is, however, a notable paucity of research utilising dMRI techniques to investigate the w..

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Awarded by National Health and Medical Research Council (NHMRC) of Australia

Funding Acknowledgements

The authors acknowledge the financial support of the HEARing CRC, established under the Cooperative Research Centres (CRC) Programme. The CRC Programme supports industry led end-user driven research collaborations to address the major challenges facing Australia. We are grateful to the National Health and Medical Research Council (NHMRC: GNT#1023372, BAN) of Australia, and the Victorian Government's Operational Infrastructure Support Program for their support. BAN is supported by a Research Fellowship from the Garnette Passe and Rodney Williams Memorial Foundation. We gratefully acknowledge Dr David Nayagam (Nestlair Photography) for provision of high-resolution images of fixed human brain tissue, and Associate Professor Jenny Hayes (Department of Anatomy and Neuroscience, University of Melbourne) for preparing the human ethics submission to facilitate this photography.