Journal article

Spatial reversal learning is robust to total sleep deprivation

Cathalijn HC Leenaars, Ruud NJMA Joosten, Michiel Kramer, Ger Post, Leslie Eggels, Mark Wuite, Maurice Dematteis, Matthijs GP Feenstra, Eus JW Van Someren

BEHAVIOURAL BRAIN RESEARCH | ELSEVIER SCIENCE BV | Published : 2012

Abstract

Sleep deprivation affects cognitive functions that depend on the prefrontal cortex (PFC) such as cognitive flexibility, and the consolidation of newly learned information. The identification of cognitive processes that are either robustly sensitive or robustly insensitive to the same experimental sleep deprivation procedure, will allow us to better focus on the specific effects of sleep on cognition, and increase understanding of the mechanisms involved. In the present study we investigate whether sleep deprivation differentially affects the two separate cognitive processes of acquisition and consolidation of a spatial reversal task. After training on a spatial discrimination between two lev..

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University of Melbourne Researchers