Journal article

Reported practice of temperature adjustment (alpha-stat v pH-stat) for arterial blood gases measurement among investigators from two major cardiac arrest trials

Glenn M Eastwood, Niklas Nielsen, Alistair D Nichol, Markus B Skrifvars, Craig French, Rinaldo Bellomo

Critical Care and Resuscitation | AUSTRALASIAN MED PUBL CO LTD | Published : 2019


BACKGROUND: Two major cardiac arrest trials are evaluating different strategies that may potentially mitigate neurological injury after cardiac arrest and are allowing co-enrolment. However, one trial will target hypothermia and the other will target mild hypercapnia, in which the carbon dioxide (CO2) measurement may be influenced by the choice of temperature adjustment during arterial blood gases (ABGs) measurement. The trials have agreed to standardise assessment by the α-stat method. OBJECTIVES: To describe the Targeted Therapeutic Mild Hypercapnia after Resuscitated Cardiac Arrest (TAME) and Targeted Hypothermia versus Targeted Normothermia after Out-of-hospital Cardiac Arrest (TTM2) sit..

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