Journal article

Influenza Epidemiology, Vaccine Coverage and Vaccine Effectiveness in Children Admitted to Sentinel Australian Hospitals in 2017: Results from the PAEDS-FluCAN Collaboration

CC Blyth, KK Macartney, J McRae, JE Clark, HS Marshall, J Buttery, JR Francis, T Kotsimbos, PM Kelly, AC Cheng, M Holmes, DE Dwyer, S Senenayake, L Cooley, L Irving, G Simpson, T Korman, ND Friedman, P Wark, A Holwell Show all

Clinical Infectious Diseases | OXFORD UNIV PRESS INC | Published : 2019

Abstract

Background In 2017, Australia experienced record influenza notifications. Two surveillance programs combined to summarize the epidemiology of hospitalized influenza in children and report on vaccine effectiveness (VE) in the context of a limited nationally funded vaccination program. Methods Subjects were prospectively recruited (April-October 2017). Case patients were children aged ≤16 years admitted to 11 hospitals with an acute respiratory illness and laboratory-confirmed influenza. Controls were hospitalized with acute respiratory illness and tested negative for influenza. VE estimates were calculated using the test-negative design. Results A total of 1268 children were hospitalized with..

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Grants

Awarded by National Health and Medical Research Council


Funding Acknowledgements

This work was supported by the Australian Government Department of Health (support to FluCAN and PAEDS), support from the National Health and Medical Research Council (partnership grant APP1113851 in support of PAEDS and fellowships to C.C.B., H.S.M., and A.C.C.), and Departments of Health in New South Wales, Victoria, Queensland, South Australia, Western Australia, and the Northern Territory (support to PAEDS).