Journal article
Leigh syndrome caused by mutations in MTFMT is associated with a better prognosis
Hannah Hayhurst, Irenaeus FM de Coo, Dorota Piekutowska-Abramczuk, Charlotte L Alston, Sunil Sharma, Kyle Thompson, Rocio Rius, Langping He, Sila Hopton, Rafal Ploski, Elzbieta Ciara, Nicole J Lake, Alison G Compton, Martin B Delatycki, Aad Verrips, Penelope E Bonnen, Simon A Jones, Andrew A Morris, David Shakespeare, John Christodoulou Show all
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY | WILEY | Published : 2019
DOI: 10.1002/acn3.725
Grants
Awarded by Wellcome Centre for Mitochondrial Research
Awarded by Medical Research Council
Awarded by MRC Centre of Neuromuscular diseases
Awarded by NIHR Clinical Lectureship in Neurology
Awarded by National Institute for Health Research (NIHR) doctoral fellowship
Awarded by Australian National Health and Medical Research Council
Awarded by Children's Memorial Health Institute
Awarded by Princes Beatrix Spierfonds
Funding Acknowledgements
The work in Newcastle was supported by the Wellcome Centre for Mitochondrial Research (203105/Z/16/Z), Newcastle University Centre for Ageing and Vitality (supported by the Biotechnology and Biological Sciences Research Council and Medical Research Council L016354), UK NIHR Biomedical Research Centre for Ageing and Age-related disease award to the Newcastle upon Tyne Hospitals NHS Foundation Trust, National Institute for Health Research (NIHR), the Lily Foundation and the UK NHS Specialist Commissioners which funds the "Rare Mitochondrial Disorders of Adults and Children" Diagnostic Service in Newcastle upon Tyne (http://www.newcastle-mitochond ria. com/). Y.S.N holds a NIHR Clinical Lectureship in Neurology (CL-2016-01-003) and was funded by the MRC Centre of Neuromuscular diseases for his PhD study (MR/K000608/1). C.L.A was the recipient of a National Institute for Health Research (NIHR) doctoral fellowship (NIHR-HCS-D12-03-04). We are extremely grateful to the members of the MRC Mitochondrial Disease Patient Cohort and staff of the NHS Highly Specialised Mitochondrial Disease Service laboratory in Newcastle. Additional research support was from grants and fellowships from the Australian National Health and Medical Research Council (GNT1068409, GNT1022896), the Victorian Government's Operational Infrastructure Support Program and the Crane and Perkins families. N.J.L. was the recipient of an Australian Postgraduate Award and an Australian Mitochondrial Disease Foundation scholarship. This work was supported by the Children's Memorial Health Institute grants: 238/16 (D.P-A) and S145/16 (E.P). H.J.M.S was supported by Princes Beatrix Spierfonds (W.OR11-24) and Stichting MetaKids grants. The views expressed are those of the authors and not necessarily of the NHS, NIHR, or Department of Health.