Antimicrobial dosing for common equine drugs: a content review and practical advice for veterinarians in Australia
LY Hardefeldt, HK Crabb, KE Bailey, JR Gilkerson, H Billman-Jacobe, GF Browning
AUSTRALIAN VETERINARY JOURNAL | WILEY | Published : 2019
BACKGROUND: Appropriate dosing with antimicrobial agents is critical for effective treatment and to prevent the development of antimicrobial resistance. METHODS: A review was undertaken of equine journal articles (Equine Veterinary Journal, Equine Veterinary Education, Australian Veterinary Journal, Australian Equine Veterinarian, Journal of Veterinary Internal Medicine and Journal of Equine Veterinary Science) between January 2015 and August 2018. Those with dosing regimens for procaine penicillin G, gentamicin or trimethoprim-sulfonamide in adult horses were examined and evaluated. Pharmacokinetics and -dynamics of these drugs were also reviewed. RESULTS & CONCLUSION: The most frequently r..View full abstract
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This research was funded by the NHMRC and the National Centre for Antimicrobial Stewardship.