Journal article
Anesthetic technique and cancer outcomes: a meta-analysis of total intravenous versus volatile anesthesia
A Yap, MA Lopez-Olivo, J Dubowitz, J Hiller, B Riedel, T Wigmore, M Ferguson, D Shan, K Yee, I Meyer, R Schier, V Gottumukkala, J Wilks, V Schick, V Hui, E Sloan, J Cata, D Buggy
Canadian Journal of Anesthesia | SPRINGER | Published : 2019
Abstract
Purpose: Cancer-related mortality, a leading cause of death worldwide, is often the result of metastatic disease recurrence. Anesthetic techniques have varying effects on innate and cellular immunity, activation of adrenergic-inflammatory pathways, and activation of cancer-promoting cellular signaling pathways; these effects may translate into an influence of anesthetic technique on long-term cancer outcomes. To further analyze the effects of propofol (intravenous) and volatile (inhalational gas) anesthesia on cancer recurrence and survival, we undertook a systematic review with meta-analysis. Source: Databases were searched up to 14 November 2018. Comparative studies examining the effect of..
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Awarded by Rheumatology Research Foundation
Funding Acknowledgements
This work is funded by the Australian and New Zealand College of Anaesthetists Foundation (18/038). Dr. Lopez-Olivo's work is supported by the Rheumatology Research Foundation. Dr. Dubowitz's work is funded by Monash University PhD and ANZCA scholarships. The authors would like to thank Greg Pratt (The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA) for support with the literature searches.